Catalogue number
PRO-235
Synonyms
Dynein light chain LC8-type 2, DNCL1B, Dlc2, MGC17810, RSPH22, 8kDa dynein light chain b, DLC8b, dynein light chain 2 cytoplasmic, radial spoke 22 homolog.
Introduction
Dyneins are multi-subunit, high molecular weight ATPases which cooperate with microtubules to create energy by altering the chemical energy of ATP into the mechanical energy of movement. DYNLL2 is a large protein complex made up of six different subunits and is in charge of a large number of intracellular movements to the minus ends of microtubules. DYNLL2 is an extremely conserved eukaryotic hub protein with dozens of binding partners and numerous roles other than being a subunit of dynein and myosin Va motor proteins.
Description
DYNLL2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 109 amino acids (1-89a.a) and having a molecular mass of 12.5kDa.
DYNLL2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
DYNLL2 protein solution (1 mg/1ml) containing 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.2M NaCl and 1mM DTT.
Stability
DYNLL2 although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.??
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
