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PURE - anti mouse CD90 - Clone G7

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PURE - anti mouse CD90 - Clone G7

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PURE - anti Mouse CD90 - G7

Reference	Size	Price	Quantity	Add to cart
MO90PU(V50)	50 μg	90,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO90PU(V500)	500 μg	265,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO90PU(V50)

50 μg

90,00 € tax excl.

MO90PU(V500)

500 μg

265,00 € tax excl.

Product Description

Clone: G7
Isotype: Rat IgG2c
Tested Applications: Flow Cytometry
Conjugated: PURE
Concentration: 0.5 mg/ml
Immunogen: Mouse T-cell hybridoma C 6/68
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD90, clone G7, is a mAb intended for RUO in the identification of cells that express CD90. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: CD90 reacts with the Thy-1.1 and Thy-1.2 alloantigens (CD90.1 and CD90.2, respectively) on thymocytes, peripheral T lymph ocytes, some intraepithelial T lymph ocytes (IEL, DEC), and neurons, but not B lymph ocytes, of all mouse strains. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of thymocytes to thymic stroma. Soluble G7 mAb stimulates murine T-cell proliferation and IL-2 secretion, via signalling through the TCR/CD3 complex. mAb G7 has been reported to promote apoptosis of thymocytes and CTL clones, as determined by morphological and biochemical criteria. The Thy-1-triggered thymocyte death was found to be developmentally regulated and targeted mainly within the CD4+CD8+CD3- and CD4+CD8+CD3lo cultured immature thymocytes. G7 antibody does not react with Thy-1 (CD90) on rat thymocytes.

Other names: Thy-1, Thy1
GeneID:
Molecular weight: 25-35 kD