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PURE - anti mouse CD357 - Clone DTA-1

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PURE - anti mouse CD357 - Clone DTA-1

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PURE - anti Mouse CD357 - DTA-1

Reference	Size	Price	Quantity	Add to cart
MO357PU(V100)	100 μg	100,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO357PU(V500)	500 μg	220,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO357PU(V100)

100 μg

100,00 € tax excl.

MO357PU(V500)

500 μg

220,00 € tax excl.

Product Description

Clone: DTA-1
Isotype: Rat IgG2b
Tested Applications: Flow Cytometry
Conjugated: PURE
Concentration: 0.5 mg/ml
Immunogen: Mouse CD25+ CD4+ T Cell Line
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: CD357 (GITR; glucocorticoid-induced TNFR-related gene) is a member of the TNF receptor superfamily, also known as TNFRSF18 and AITR (in humans). It is expressed at low levels on resting T lymph ocytes and at high levels on CD25+ CD4+ Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-?B activation, and abrogate the inhibitory function of CD25+ CD4+ Tregs. In vivo activation of GITR causes development of autoimmune diseases and restores the suppressed immune response.

Other names: Glucocorticoid-induced TNFR -related gene, TNFRSF18
GeneID:
Molecular weight: 70 kD