久久久久久久久久久久久久99,五月婷婷日,六月丁香激情五月天

您好，歡迎來到拜力生物網(wǎng)站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產(chǎn)品： ELISA試劑盒、抗體、補體血清、兔補體、干擾素、小鼠測溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁 > 產(chǎn)品中心 > Immunostep > Immunostep產(chǎn)品

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

APC - anti mouse CD279 - Clone J43.1

品牌：Immunostep

貨號：

規(guī)格：

貨期：

應(yīng)用：

咨詢客服

立即購買加入購物車

APC - anti mouse CD279 - Clone J43.1

商品詳情參考文獻(xiàn) 相關(guān)資料

APC - anti Mouse CD279 - J43.1

Reference	Size	Price	Quantity	Add to cart
MO279A(V25)	25 μg	89,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO279A(V100)	100 μg	220,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO279A(V25)

25 μg

89,00 € tax excl.

MO279A(V100)

100 μg

220,00 € tax excl.

Product Description

Clone: J43.1
Isotype: Armenian Hamster IgG2
Tested Applications: Flow Cytometry
Conjugated: APC
Concentration: 0.2 mg/ml
Immunogen: Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD279, clone J43.1, is a mAb intended for RUO in the identification/enumeration of lymph that express CD279. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

View larger

Large description: CD297 (PD-1) is a 50-55-kDa glycoprotein encoded by the Pdcd1 gene of the CD28 family of the Ig superfamily. The expression of Pdcd1 mRNA and PD-1 protein is tightly regulated. PD-1 is transiently expressed on CD4-CD8thymocytes, it is upregulated on some cell lines upon induction of apoptosis, it is induced on thymocytes and splenic T and B lymph ocytes after stimulation through their antigen receptors, and it is induced on activated myeloid cells. In addition, Pdcd1 mRNA is transiently expressed in developing B lymph ocytes at the pro-B-cell stage. The presence of an ITIM (Immunoreceptor Tyrosine-based Inhibitory Motif) on PD-1's intracytoplasmic region and the development of splenomegaly and breakdown of peripheral tolerance in PD-1[-/-] mice suggest that PD-1 may be involved in the negative regulation of immune responses. The PD-1 ligands, B7-H1 (also known as PD-L1) and B7-DC (PD-L2), are members of the B7 family of the Ig superfamily. The J43 antibody blocks the binding of PD-1 to its two ligands.

GeneID: 18566
Molecular weight: 50-55 kD

熱銷產(chǎn)品