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PE - anti mouse CD19 - Clone 1D3

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PE - anti mouse CD19 - Clone 1D3

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PE - anti Mouse CD19 - 1D3

Reference	Size	Price	Quantity	Add to cart
MO19PE(V25)	25 μg	65,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO19PE(V100)	100 μg	175,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO19PE(V25)

25 μg

65,00 € tax excl.

MO19PE(V100)

100 μg

175,00 € tax excl.

Product Description

Clone: 1D3
Isotype: IgG2a
Tested Applications: Flow Cytometry
Conjugated: PE
Concentration: 0.2 mg/ml
Immunogen: Mouse CD19-transfected cell line
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

Large description: CD19, a 95-kDa transmembrance glycoprotein, is a member of the immunoglobulin superfamily and is expressed throughout B-lymph ocyte development from the pro-B cell throughthe mature B-cell stages. Terminally differentiated plasma cells do not express CD19. On the surface of mature B cells, the CD19 molecule associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to promote cellular activation. Studies with CD19-deficient mice have suggested that the level of CD19 expression affects the generation and maturation of B cells in the bone marrow and periphery. B-1 lineage B cells, also known as CD5+ B cells, are drastically reduced or absent in CD19-deficient mice. Increased levels of CD19 expression correlate with increased frequencies of peritonal and splenic B-1 cells and reduced numbers of conventional B lymph ocytes in the periphery. CD19 participates in B-lymph ocyte development, B-cell activation, maturation of memory B cells and regulation of tolerance. CD19 has also been detected on peritoneal mast cells, co-localized with CD21/CD35, and it is proposed to play a role in complement-mediated mast-cell activation.

Other names: B4
GeneID:
Molecular weight: 95 kD