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PURE - anti mouse CD152 - Clone UC10-4F10-11

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PURE - anti mouse CD152 - Clone UC10-4F10-11

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PURE - anti mouse CD152 - Clone UC10-4F10-11

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PURE - anti Mouse CD152 - UC10-4F10-11

Reference	Size	Price	Quantity	Add to cart
MO152PU(V100)	100 μg	100,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO152PU(V500)	500 μg	220,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO152PU(V100)

100 μg

100,00 € tax excl.

MO152PU(V500)

500 μg

220,00 € tax excl.

Product Description

Clone: UC10-4F10-11
Isotype: Armenian Hamster IgG
Tested Applications: Flow Cytometry
Conjugated: PURE
Concentration: 0.5 mg/ml
Immunogen: Mouse CTLA-4 IgG2a Fusion
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD152, clone UC10-AF10-11, is a mAb intended for RUO in the identification/enumeration of lymph that express CD152. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: CD152 also known as, Cytotoxic T-lymph ocyte-associated antigen 4 (CTLA-4). CD152 is expressed on activated T lymph ocytes 2-3 days after stimulation through T cell receptor. CTLA-4 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. Whereas CD28 delivers a costimulatory signal required for T-cell activation, CTLA-4 is a negative regulator of cell-mediated immune responses. CD152 may play roles in induction and/or maintenance of immunological tolerance, regulation of protective immunity, and autoimmune responses, and regulation of some aspects of thymocyte maturation. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leucocytes.

Other names: Ctla4; CTLA-4; Cytotoxic T-lymph ocyte-associated protein 4; Ly-56
GeneID: 12477
Molecular weight: 33 kD