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APC - anti mouse CD115 - Clone CSF-1R

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APC - anti mouse CD115 - Clone CSF-1R

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APC - anti Mouse CD115 - CSF-1R

Reference	Size	Price	Quantity	Add to cart
MO115A(V25)	25 μg	90,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO115A(V100)	100 μg	275,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO115A(V25)

25 μg

90,00 € tax excl.

MO115A(V100)

100 μg

275,00 € tax excl.

Product Description

Clone: CSF-1R
Isotype: Rat IgG2a
Tested Applications: Flow Cytometry
Conjugated: APC
Concentration: 0.2 mg/ml
Immunogen: Mouse CD115 Recombinant Protein
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: CD115 is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

Other names: CSF-1R, M-CSFR, c-fms
GeneID:
Molecular weight: 145 kD