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PURE - anti human CD57 - Clone HI57a

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PURE - anti human CD57 - Clone HI57a

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PURE - anti Human CD57 - HI57a

Reference	Size	Price	Quantity	Add to cart
57PU-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

57PU-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: HI57a
Isotype: IgM
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Human neuroblastoma cells
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD57, clone HI57a, is a mAb valid for the for identification of antigen CD57 expressed on a subset of NK cells and NK T cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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Large description: This antibody reacts with the CD57-antigen, a carbohydrate antigen present on a subset of peripheral blood mononuclear cells involved in the Natural Killer activity, which is not MHC restricted. The antigen is not present on B cells, monocytes, red blood cells or platelets but is expressed on cells in neuroectodermal tissue. It reacts with 20% of normal human peripheral blood mononuclear cells. Reacts with a 110 kDa carbohydrate antigen associated with myelin-associated glycoprotein expressed on 7-35% of normal peripheral blood lymphocytes including a subset of natural killer cells, a subset of CD8+ peripheral blood suppressor/cytotoxic T cells, and on some neural tissues. CD57 is not expressed on granulocytes, platelets, red blood cells or thymocytes. The function of CD57 is still unclear, however, its expression on T-cell subets occurs in late immune responses.

Other names: HNK-1, NK-1, Leu-7
GeneID: 27087
Molecular weight: 110 kDa