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PURE - anti human CD56 - Clone MEM-188

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PURE - anti human CD56 - Clone MEM-188

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PURE - anti Human CD56 - MEM-188

Reference	Size	Price	Quantity	Add to cart
56PU2-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

56PU2-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: MEM-188
Isotype: IgG1
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: KG-1 human acute myelogenous leukemia cell line
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD56, clone MEM-118, is a mAb valid for identification of Natural Killer (NK) Cells and a subpopulation of T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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Large description: This antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested. CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.

Other names: Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5, He11
GeneID: 4684
Molecular weight: 175-185kDa