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PURE - anti human CD56 - Clone B-A19

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PURE - anti human CD56 - Clone B-A19

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PURE - anti Human CD56 - B-A19

Reference	Size	Price	Quantity	Add to cart
56PU1-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

56PU1-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: B-A19
Isotype: IgG1
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: U937 cell line (Human)
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD56, clone B-A19, is a mAb valid for identification of Natural Killer (NK) Cells and a subpopulation of T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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Large description: This antibody reacts with the CD56-antigen, which is expressed in lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors. It is expressed on natural killer (NK) Cells and a subpopulation of T lymphocytes. NK cells make up approximately 10-25% of peripheral blood lymphocytes. This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Expression of neural cell adhesion molecules (N-CAM) provides neurons with a means of attaching to and interacting with other cells and the extracellular matrix. There are describes 6 isoforms produced by alternative splicing of N-CAM mRNA. The three major isoforms are referred to as 180 kD, 140 kD, and 120 kD. Individual isoforms undergo various post-translational modifications, including the addition of polysialic acid residues to embryonic forms. The highly polysialylated forms of N-CAM present in embryos and neonates are lost during maturation and replaced by less-polysialic acid-laden mature forms of N-CAM. The functional significance of alternative forms of N-CAM remain to be fully elucidated.

Other names: Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5, He6
GeneID: 4684
Molecular weight: 175-185kDa