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PURE - anti human CD52 - Clone HI186

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PURE - anti human CD52 - Clone HI186

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PURE - anti Human CD52 - HI186

Reference	Size	Price	Quantity	Add to cart
52PU-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

52PU-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: HI186
Isotype: IgG2b
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Tissue / cell preparation (Human tonsil).
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:

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Large description: This antibody reacts with the CD52-antigen (also known as CAMPATH-1), a protein of 6,6 kDa. It is expressed on male reproductive tract (epididymis, seminal vesicle), thymocytes, eosinophils, lymphocytes, red cells, monocytes and macrophages, but not on plasma cells, platelets or erythrocytes. CD52 plays a role in carrying and orienting carbohydrate. This molecule is expressed on lymphoid malignancies at variable levels and on epithelial cells of the epididymis and seminal vesicles. Its functional role is not well known but reports indicate that CD52 is a good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Antibodies to CD52 have been studied in lymphocyte depletion experiments. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.

Other names: CDw52, Cambridge pathology 1 antigen, CAMPATH-1 antigen, Epididymal secretory, protein E5, Human epididymis-specific protein 5, He5
GeneID:
Molecular weight: 25-29 kDa