五月天六月激情,丁香五月婷好骚,九九99热久久999精品

您好，歡迎來(lái)到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線(xiàn)客服QQ：3012681483 | 客服電話(huà)：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Immunostep > Immunostep產(chǎn)品

Biotin - anti human CD49d - Clone ALC1/1

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Biotin - anti human CD49d - Clone ALC1/1

品牌：Immunostep

貨號(hào)：

規(guī)格：

貨期：

應(yīng)用：

咨詢(xún)客服

立即購(gòu)買(mǎi) 加入購(gòu)物車(chē)

Biotin - anti human CD49d - Clone ALC1/1

商品詳情參考文獻(xiàn) 相關(guān)資料

Biotin - anti Human CD49d - ALC1/1

Reference	Size	Price	Quantity	Add to cart
49DB-01MG	100 μg	180,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

49DB-01MG

100 μg

180,00 € tax excl.

Product Description

Clone: ALC1/1
Isotype: IgG1
Tested Applications: FCM
Conjugated: Biotin
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Tissue / cell preparation (JM leukemia line).
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD49b, clone ALC1/1 is a mAb primarily expressed on T and B lymphocytes and weakly expressed on monocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

View larger

Large description: This antibody reacts with the CD49d antigen, which recognizes the 150-kilodalton (kd) α-chain of very-late antigen (VLA)-4, a member of the integrin family of cell adhesion molecules. VLA-4, like other integrins, is a noncovalently associated heterodimeric glycoprotein composed of α and ? subunits and is involved in cell–cell and cell–extracellular matrix interactions. The ?-chain of the VLA-4 complex is the CD29 antigen, a 130-kd glycoprotein. The CD29 antigen, also known as the ?-1 subunit, is common to the VLA family of integrins. When acting as a matrix receptor, the CD49d antigen binds to CS-1, an alternatively spliced domain of fibronectin. When functioning as a cell receptor, the CD49d antigen binds to the vascular cell-adhesion molecule-1 (VCAM-1). The interaction between the CD49d antigen and VCAM-1 is known to play an important role in stabilizing the adhesion of lymphocytes to endothelial cells and in mediating B-lymphocyte precursor/bone marrow stromal cell adhesion. The CD49d antigen, when associated with the ? integrin, forms a lymphocyte homing receptor for Peyer's patch, binding tothe mucosal vascular addressin MAdCAM-1. The CD49d antigen is also involved in CD3-dependent CD4+ T-lymphocyte activation via its interaction with fibronectin.

Other names: Alpha-4 integrin chain; VLA-4 alpha chain, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha
GeneID: 3676
Molecular weight: 150 kDa