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PURE - anti human CD22 - Clone HIB22

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PURE - anti human CD22 - Clone HIB22

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PURE - anti Human CD22 - HIB22

Reference	Size	Price	Quantity	Add to cart
22PU-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

22PU-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: HIB22
Isotype: IgG1
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Hairy Cell Leukemia cells
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD22, clone HIB22 is a mAb intended for identification/enumeration of B cells subsets, so much mature as late pro- and early pre-B cells by FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
Storage Instruction: Store in the dark at 2-8 °C

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Large description: This antibody reacts with the CD22-antigen, which is expressed on human B lymphocytes. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation.

Other names: B-cell receptor CD22, B-lymphocyte cell adhesion molecule (BL-CAM), Sialic acid-binding Ig-like lectin 2 (Siglec-2), T-cell surface antigen Leu-14, SIGLEC-2, SIGLEC2, Lyb8
GeneID: 933
Molecular weight: 130 - 140 kDa