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PURE - anti human CD21 - Clone HI21a

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PURE - anti human CD21 - Clone HI21a

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PURE - anti Human CD21 - HI21a

Reference	Size	Price	Quantity	Add to cart
21PU-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

21PU-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: HI21a
Isotype: IgG2a
Tested Applications: FCM
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Tissue / cell preparation (Human).
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD21, clone HI21a is a mAb intended for identification/enumeration of mature B cells, follicular dendritic cells and epithelial cells by FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
Storage Instruction: Store in the dark at 2-8 °C

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Large description: This antibody reacts with the CD21-antigen, which reacts with the C3d complement fragment and with Epstein Barr virus (EBV) receptors, found on mature B cells, follicular dendritic cells, andsome epithelial cells. It is also weakly expressed on a subset of mature T cells and thymocytes. This clone also cross-reacts with a major subset of, but not all, peripheral blood CD20 + lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. A subset of CD3 + cells is also CD21 +. The monoclonal antibody is directed against the CD21-antigen, which is expressed on normal Ig-positive B-cells from peripheral blood and lymphoid tissues and on dendritic cells of germinal centres. Its expression is lost on activated B-cells. The distinct distribution among B-cell malignancies differs from other B-cell markers e.g. CD19 and CD20

Other names: Complement receptor type 2 (Cr2), Complement C3d receptor, Epstein-Barr virus receptor (EBV receptor), C3DR
GeneID: 1380
Molecular weight: 145 kDa