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Biotin - anti human CD16 - Clone 3G8

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Biotin - anti human CD16 - Clone 3G8

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Biotin - anti Human CD16 - 3G8

Reference	Size	Price	Quantity	Add to cart
16B2-01MG	100 μg	180,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

16B2-01MG

100 μg

180,00 € tax excl.

Product Description

Clone: 3G8
Isotype: IgG1
Tested Applications: FCM
Conjugated: Biotin
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Human polymorphonuclear leukocytes
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:
Storage Instruction: Store in the dark at 2-8 °C

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Large description: This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.

Other names: FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR9
GeneID:
Molecular weight: 50-65 kDa