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APC - anti human CD123 - Clone AC145

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APC - anti human CD123 - Clone AC145

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APC - anti Human CD123 - AC145

Reference	Size	Price	Quantity	Add to cart
123A-100T	100 test	450,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

123A-100T

100 test

450,00 € tax excl.

Product Description

Clone: AC145
Isotype: IgG2a
Tested Applications: FCM
Conjugated: APC
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD123, clone AC145, is a mAb intended for the identification of DCs. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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Large description: This antibody reacts with the CD123 antigen, the α chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common β chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes. At the level of the hematopoietic system IL-3R alpha expression was described on bone marrow CD34+ cells (including primitive multipotential and committed progenitors), granulocytes, monocytes/macrophages, megakaryocytes and B-lymphocytes. Although the IL-3R alpha is expressed on the large majority of progenitor cells, it does not seem to be expressed on the stem cell fraction.

Other names: IL-3R, CDw123, Interleukin-3 receptor subunit alpha,
GeneID: 3563
Molecular weight: 41 KDa