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PURE - anti human CD105 - Clone 2H6F11

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PURE - anti human CD105 - Clone 2H6F11

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PURE - anti Human CD105 - 2H6F11

Reference	Size	Price	Quantity	Add to cart
105PU-01MG	100 μg	130,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

105PU-01MG

100 μg

130,00 € tax excl.

Product Description

Clone: 2H6F11
Isotype: IgG1
Conjugated: PURE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: Human Endoglin fusion protein
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD105, clone 2H6F11 is a mAb intended for identify Endothelial cells, activated monocytes/macrophages, BM stromal cells, HCs stem/progenitor cells. It is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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Large description: This antibody reacts with the CD105 antigen, which is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta, Pre-B cells in fetal marrow, erythroid precursors in fetal and ***** bone marrow and is weakly expressed by stromal fibroblasts. Reacts with a homodimeric integral membrane protein comprised of 95Kd subunits (CD105). CD105 is a component of the TGF-B receptor system and can bind TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. U937 cells and monocytes and tissue macrophages also expresses CD105. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumours, or in cases of wound healing or dermal inflammation.

Other names: Endoglin
GeneID: 2022
Molecular weight: 95 kD