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Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).

Target	UNC5C
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human UNC5C.
Purification	Peptide Affinity Purified Rabbit Polyclonal Antibody.
Isotype	IgG
Conjugation	Unconjugated
Specificity	This UNC5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the N-terminal region of human UNC5C.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O95185
Gene Symbol	UNC5C
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.