POU2AF1 is transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
Target
POU2AF1
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Tested Applications
IHC
Recommended dilutions
Optimal dilutions/concentrations should be determined by the end user.
This POU2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human POU2AF1.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot
Q16633
Buffer
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.