This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Target
BCL2
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Tested Applications
WB
Recommended dilutions
Optimal dilutions/concentrations should be determined by the end user.
This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the Central region of human BCL2.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot
P10415
Buffer
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.