Phospho-Merlin (Ser518) Antibody detects endogenous levels of Merlin only when phosphorylated at Serine 518. This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.
Target
Merlin (pS518)
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Tested Applications
WB
Recommended dilutions
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen
A synthesized peptide derived from human Merlin around the phosphorylation site of Serine 518.
Purification
Immunogen affinity purified.
Conjugation
Unconjugated
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight
70 kDa
Swiss Prot
P35240
Buffer
Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.