GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9.? Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers.? GDF-3 is expressed in ***** bone marrow, spleen, thymus, and adipose tissue.? The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes.? Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
Manufactured using all Animal-Free reagents.
Source: E.coli
Synonyms: Growth/Differentiation Factor-3, Vgr-2, UNQ2222/PRO248
AA Sequence (monomer): AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.? The ED50 for this effect is 100-150 ng/ml.
BIOLEAF熱搜 BIOLEAF試劑盒 BIOLEAF ELISA BIOLEAF試劑 BIOLEAF品牌 BIOLEAF抗體 BIOLEAF耗材 BIOLEAF小儀器
sitemap 細胞庫查詢 危險品圖標(biāo) 本公司網(wǎng)站所展示銷售的產(chǎn)品僅供科研！
滬公網(wǎng)安備 31011202007338號
