All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO/MGSA is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.
Manufactured using all Animal-Free reagents.
Source: E.coli
Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity, MGSAα, NAP-3, GRO1
AA Sequence: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Not available.
Note:
1mg will be provided as 2x500μg.
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