HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues, including skeletal muscle, heart, spleen, liver, bone marrow and plasma. Mature HCC-1 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66 amino acid residues. Recombinant Human HCC-1 (66 a.a.) is a 7.8 kDa protein consisting of 66 amino acids, including the four highly conserved residues present in CC chemokines.
Source:
E.coli
Synonyms:
Hemofiltrate CC Chemokine-1, CCL14, HCC-1/HCC-3, NCC-2
AA Sequence:
GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Purity:
≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml.
