IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids.? Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II.? IGF-BP2 is a cysteine-rich, secreted protein produced by bone cells, and is most abundant in the brain.? IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells.? Recombinant Human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.
Source: (BTI-Tn-5B1-4) Hi-5 Insect cells
Synonyms: Insulin-like Growth Factor-Binding Protein 2, IBP-2
AA Sequence: EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Note:
1mg will be provided as 2x500μg.
BIOLEAF熱搜 BIOLEAF試劑盒 BIOLEAF ELISA BIOLEAF試劑 BIOLEAF品牌 BIOLEAF抗體 BIOLEAF耗材 BIOLEAF小儀器
sitemap 細(xì)胞庫查詢 危險(xiǎn)品圖標(biāo) 本公司網(wǎng)站所展示銷售的產(chǎn)品僅供科研！
滬公網(wǎng)安備 31011202007338號(hào)
