IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.? IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response.? IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.? Recombinant Rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues.
Manufactured using all Animal-Free reagents.
Source: E.coli
Synonyms: T-cell growth factor (TCGF), Aldesleukin
AA Sequence: MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: The ED50?as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is?≤ 0.4 ng/ml, corresponding to a specific activity of?≥ 2.5 x 106?units/mg.
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