IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.? Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.? Human and murine IL-7 is cross-species reactive.? Recombinant Rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.