PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, the colon, and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. Recombinant Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains.
Source: E.coli
Synonyms: Placenta Growth Factor-1, PlGF, PGF
AA Sequence (monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR
Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.
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