MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog.? MIP-1γ signals through the CCR1 receptor.? MIP-1γ chemoattracts neutrophils, and also inhibits colony formation of bone marrow myeloid immature progenitors.? MIP-1γ contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines.? Recombinant Murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
Source: E.coli
Synonyms: Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18
AA Sequence: QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.
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