MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells.? It signals through the CXCR3 receptor.? MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors.? Human MIG is active on murine cells.? Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.
Source: E.coli
Synonyms: Monokine Induced by Interferon-gamma, CXCL9
AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml.
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