The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines.
Source:
E.coli
Synonyms:
Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)
AA Sequence:
QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEWV QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLTHKS EANASTLFST TTSSTSVEVT SMTEN
Purity:
≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Note:
1mg will be provided as 2x500μg.
