您好，歡迎來到拜力生物網(wǎng)站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁 > 產(chǎn)品中心 > EuroDiagnostica > EuroDiagnostica產(chǎn)品

iLite? GM-CSF Assay Ready Cells (BM4050)

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

iLite? GM-CSF Assay Ready Cells (BM4050)

品牌：Svar Life Science

貨號：

規(guī)格：

貨期：

應(yīng)用：

咨詢客服

立即購買加入購物車

iLite? GM-CSF Assay Ready Cells (BM4050)

商品詳情參考文獻(xiàn) 相關(guān)資料

iLite? GM-CSF Assay Ready Cells

Add to my product list

iLite^? GM-CSF Assay Ready Cells are a genetically engineered reporter gene cell line (U937, ATCC# CRL1593.2) responsive to granulocyte-macrophage colony-stimulating factor (GM-CSF) by specific and proportional expression of Firefly Luciferase. Normalization of cell counts and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under the control of a constitutive promotor.

Product code

BM4050

Format

Assay Ready Cells

Calculation

Quantitative

Antigen

GM-CSF

Detection system

Luminescence

Availability

Research use only

Application
Background
Content

The iLite^? GM-CSF Assay Ready Cells can be used for the quantification GM-CSF activity, GM-CSF inhibitor activity, and for determination of neutralizing antibodies against such either in buffer systems or human serum.

? Quantification of GM-CSF activity using iLite^? GM-CSF Assay Ready Cells (E-220-GB)

? Determination of GM-CSF neutralizing activity using iLite^? GM-CSF Assay Ready Cells (E-221-GB)

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine which stimulates the production of granulocytes and monocytes from bone marrow precursors (1). As such, it serves as an important key in both humoral and cell mediated immunity. Recombinant GM-CSF has several therapeutic uses; in order to accelerate leukocyte recovery after bone marrow transplantation, to replenish leukocytes after chemotherapy and for treatment of fungal infections.

The immunostimulatory effects of GM-CSF have also been used in oncolytic viruses modified to include genes coding for GM-CSF, thus enhancing recruitment of the immune response to tumor cells. In addition, the discovery of a pro-inflammatory role of GM-CSF in autoimmune disease has led to development of several GM-CSF inhibitor drugs (2, 3).

>250 μL of iLite^? Assay Ready Cells suspended in RPMI 1640 with 20% FBS, mixed 1:1 with cryoprotective medium from Lonza (Cat. No 12-132A).

熱銷產(chǎn)品