Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. The product can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
Cell Types
Expressed in the proliferating cells of the developing CNS and the epidermis.
Protein Location
Nucleus
Gene Type
cDNA
Purification
By Ion-Exchange column.
Quality Control
By sequencing and Western blot analysis of transgene expression in transduced cells. Functional test includes iPSC reprogramming.
Titer
>1x106pfu/mL
Storage
10 mM Tris-HCl, pH 8.0
Shipping
High titer adenoviruses are shipped with dry ice and low titer adenoviruses are shipped with ice packs. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles.
Notes
For Research Use Only, not for therapeutic or diagnostic purposes.