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Recombinant Human CXCL11

品牌：Abmgood

貨號：Z100585

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Recombinant Human CXCL11

商品詳情參考文獻(xiàn) 相關(guān)資料

	Print Version
Alternative Names	CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11 Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11)
Description	The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3).
Gene Symbol	CXCL11
Gene ID	6373
Accession No.	O14625
Source	E. coli
Appearance	Lyophilized Powder
Molecular Weight	8.0 kDa
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity	>95% as determined by SDS-PAGE
Gel Image
Bioactivity	Determined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL
Bioactivity Data
Formulation	Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5
Reconstitution	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage	For research use only. Not for diagnostic or therapeutic use.