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Recombinant Human NRG1

品牌：Abmgood

貨號：Z101629

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Recombinant Human NRG1

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	Print Version
Alternative Names	Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor Recombinant Human Neuregulin-1 Beta (NRG1)
Description	Neuregulins are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
Gene Symbol	NRG1
Gene ID	3084
Accession No.	Q02297
Source	E. coli
Appearance	Lyophilized Powder
Molecular Weight	7.0 kDa
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity	>95% as determined by SDS-PAGE
Bioactivity	The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be < 0.3 ng/mL, corresponding to a specific activity of 2.0 x 10^6 Units/mg.
Formulation	Recombinant Neuregulin-1 was lyophilized from a 0.2 μm filtered 10mM PB, pH 7.0, containing 2% mannitol, 0.5% HSA.
Reconstitution	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage	For research use only. Not for diagnostic or therapeutic use.