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Amidepsine A

品牌：AG Scientific

貨號：

規(guī)格：1 mg

貨期：

應(yīng)用：

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Formula:C29H29NO11MW:567.6Appearance:WhitetoPaleYellowPowderPurity:95%(HPLC)

商品詳情參考文獻相關(guān)資料

Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC=10.2 M) and Raji cells (IC=15.5 M). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

Additional Information

Product #	A-1430
Chemical Name	2,4-DIMETHOXY-6-METHYL-BENZOIC ACID 4-[[4-[[(1-CARBOXYETHYL)AMINO]CARBONYL]-3-HYDROXY-5-METHYLPHENOXY]CARBONYL]-3-HYDROXY-5-METHYLPHENYL ESTER
Formula	C₂₉H₂₉NO₁₁
MW	567.6
Appearance	White to Pale Yellow Powder
Purity	95% (HPLC)
Solubility	Soluble in methanol or ethyl acetate; insoluble in water.
Storage Temp	-20°C
Therapeutic Area	Vascular Disorders
Use	Amidepsine A is an inhibitor of DGAT (diacylglycerol acyltransferase) use in atherosclerosis, diabetes and metabolic disorders

Additional Information

MDL Number	MFCD28138425
InChI	InChI=1S/C29H29NO11/c1-13-8-18(10-20(31)23(13)26(33)30-16(4)27(34)35)40-28(36)24-14(2)9-19(11-21(24)32)41-29(37)25-15(3)7-17(38-5)12-22(25)39-6/h7-12,16,31-32H,1-6H3,(H,30,33)(H,34,35)
SMILES	CC1=CC(=CC(=C1C(=O)NC(C)C(=O)O)O)OC(=O)C2=C(C=C(C=C2C)OC(=O)C3=C(C=C(C=C3C)OC)OC)O

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