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A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Additional Information

Synonyms	Boc-D-FMK, Caspase Inhibitor (fluoromethylketone)
Product #	D-2289
Chemical Name	(S)-METHYL 3-(TERT-BUTOXYCARBONYLAMINO)-5-FLUORO-4-OXOPENTANOATE
Formula	C11H18FNO5
MW	263.26
Appearance	Lyophilized Solid
Purity	95% by HPLC
Solubility	DMSO (20 mM)
Storage Temp	-20°C

Additional Information

MDL Number	MFCD03453073
ChemACX	X1341018-5
InChI	InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)
SMILES	CC(C)(C)OC(=O)NC(CC(=O)OC)C(=O)CF