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S-Trityl-L-cysteine

品牌：AG Scientific

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規(guī)格：100 mg

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CAS:2799-07-7Formula:C22H21NO2SMW:363.5Appearance:Whitetooff-whiteSolid

商品詳情參考文獻(xiàn) 相關(guān)資料

Potent, cell permeable cysteine thioether displaying anti-mitotic and anti-tumor properties. Inhibits mitosis by blocking basal and microtubule-activated ATPase activities of the mitotic kinesin Eg5 (IC50=1 uM and 140nm). Induces mitotic arrest in HeLa cells (IC50=700nM) and inhibits the growth of NCI tumor cell line panel (GI50=1.31 uM).

Additional Information

Synonyms	Trityl-cysteine, NSC 83265
Product #	T-1186
CAS #	2799-07-7
Chemical Name	(2R)-2-AMINO-3-TRITYLSULFANYLPROPANOIC ACID
Formula	C₂₂H₂₁NO₂S
MW	363.5
Appearance	White to off-white Solid
Solubility	Soluble in DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	S-Trityl-L-cysteine is a cell-permeable cysteine thioether compound that exhibits antitumor and antimitotic properties by inhibiting mitotic kinesin Eg5

Additional Information

MDL Number	MFCD00002611
ChemACX	X1014343-0
InChI	InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1
SMILES	c1ccc(cc1)C(c2ccccc2)(c3ccccc3)SC[C@@H](C(=O)O)N

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