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*Please inquire the availability for this product. Demeclocycline hydrochloride is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.

Additional Information

Synonyms	6-Demethylchlotetracycline hydrochloride, 7-Chloro-6-demethyltetracycline hydrochloride, Declomycin, Ledermycin hydrocloride, RP 10192
Product #	D-2485
CAS #	64-73-3
Formula	C21H22Cl2N2O8
MW	501.3
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Solubility	Soluble in water (20 mg/ml), DMSO, and methanol
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Use for the treatment of infections caused by tetracycline-sensitive organisms

Additional Information

MDL Number	MFCD00082371
InChI	InChI=1S/C21H21ClN2O8.ClH/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H/t6-,7-,14-,15-,21-;/m0./s1
SMILES	CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O.Cl