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A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.

Additional Information

Synonyms	Butyric acid, Sodium salt, NaB
Product #	S-2438
CAS #	156-54-7
Chemical Name	Butyric acid, Sodium salt, NaB
Formula	C4H7O2 Na
MW	110.1
Appearance	White Solid
Purity	99% by HPLC
Solubility	Soluble in H2O (100 mM)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	An HDAC inhibitor and apoptosis inducer in cancer cell

Additional Information

MDL Number	MFCD00002816
ChemACX	X1001036-5
InChI	InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
SMILES	CCCC(=O)[O-].[Na+]