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*Please inquire the availability for this product. Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

Additional Information

Synonyms	6-Demethyl-6-deoxytetracycline, Bonomycin, Norcycline
Product #	S-2751
CAS #	808-26-4
Formula	C21H22N2O7
MW	414.4
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMSO, DMF Limited water solubility
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Sancycline is a antibiotic

Additional Information

MDL Number	MFCD00864992
InChI	InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
SMILES	CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4cccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O