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BEZ235

品牌：AG Scientific

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規(guī)格：5 mg

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CAS:915019-65-7Formula:C30H23N5OMW:469.55Appearance:Off-whitetopaleyellowSolidPurity:99%byHPLC

商品詳情參考文獻(xiàn) 相關(guān)資料

Orally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition; BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.

Additional Information

Synonyms	NVP-BEZ235
Product #	B-2199
CAS #	915019-65-7
Chemical Name	2-METHYL-2-[4-[3-METHYL-2-OXO-8-(QUINOLIN-3-YL)-2,3-DIHYDROIMIDAZO[4,5-C]QUINOLIN-1-YL]PHENYL]PROPIONITRILE
Formula	C₃₀H₂₃N₅O
MW	469.55
Appearance	Off-white to pale yellow Solid
Purity	99% by HPLC
Solubility	DMSO (10 mM)
Melting Point	288-289 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	BEZ235 is a PI 3-kinase (PI3K) tyrosine kinase inhibitor and mTOR inhibitor in cancer

Additional Information

MDL Number	MFCD10565944
ChemACX	X1722298-9
InChI	InChI=1S/C30H23N5O/c1-30(2,18-31)22-9-11-23(12-10-22)35-28-24-15-19(21-14-20-6-4-5-7-25(20)32-16-21)8-13-26(24)33-17-27(28)34(3)29(35)36/h4-17H,1-3H3
SMILES	CC(C)(C#N)c1ccc(cc1)n2c3c4cc(ccc4ncc3n(c2=O)C)c5cc6ccccc6nc5

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