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3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata

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3-O-Acetyl-11-keto-Beta-boswellic acid, Boswellia serrata

品牌：AG Scientific

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規(guī)格：5 mg

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CAS:67416-61-9Formula:C32H48O5MW:512.7Appearance:Whitetooff-whiteSolidPurity:99%byHPLC,NMR

商品詳情參考文獻(xiàn) 相關(guān)資料

Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis. Mobilizes intracellular Ca2+ and potently inhibits the MAP kinases p38 and p44/42. 10-times more potent than 3-O-Acetyl-boswellic acid. Has been shown to exhibit in vivo efficacy in tumor growth and inhibition.

Additional Information

Product #	B-1265
CAS #	67416-61-9
Chemical Name	(3R,4R,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BS)-3-ACETYLOXY-4,6A,6B,8A,11,12,14B-HEPTAMETHYL-14-OXO-1,2,3,4A,5,6,7,8,9,10,11,12,12A,14A-TETRADECAHYDROPICENE-4-CARBOXYLIC ACID
Formula	C₃₂H₄₈O₅
MW	512.7
Appearance	White to off-white Solid
Purity	99% by HPLC, NMR
Solubility	Soluble in acetone, dichloromethane, diethyl ether or DMSO.
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Potent non-redox, noncompetitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis which shows anti-tumor and anti-inflammatory activities

Additional Information

MDL Number	MFCD03788777
ChemACX	X1618870-0
InChI	InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)/t18-,19+,23-,24-,25+,26-,28-,29+,30-,31-,32-/m1/s1
SMILES	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C

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