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A potent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. ICvalues are 0.20 and 0.24 M for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo.

Additional Information

Synonyms	1,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimid in-4-one
Product #	D-2297
CAS #	284028-90-6
Chemical Name	1,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimid in-4-one
Formula	C8H10N2OS
MW	182.24
Appearance	Off-white to white Solid
Purity	98% by HPLC
Solubility	Soluble in H2O (40 mM)
Storage Temp	-20°C
Therapeutic Area	Neurological Disorders
Use	A competitive and water soluble PARP inhibitor

Additional Information

MDL Number	MFCD08703132
ChemACX	X1579392-1
InChI	InChI=1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
SMILES	CC1=NC(=O)C2=C(N1)CCSC2