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Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, non-competitive 5-lipoxygenase and topoisomerase I and IIa inhibitor leading to apoptosis. Mobilizes intracellular Ca2+ and potently inhibits the MAP kinases p38 and p44/42. 10-100 times more potent than natural boswellic acid.

Additional Information

Synonyms	A-beta-BA
Product #	B-1263
CAS #	5968-70-7
Chemical Name	(3R,4R,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BR)-3-ACETYLOXY-4,6A,6B,8A,11,12,14B-HEPTAMETHYL-2,3,4A,5,6,7,8,9,10,11,12,12A,14,14A-TETRADECAHYDRO-1H-PICENE-4-CARBOXYLIC ACID
Formula	C32H50O4
MW	498.8
Appearance	White to off-white Solid
Purity	98% by HPLC
Solubility	Soluble in DMSO; sparingly soluble in water.
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A non-competitive 5-lipoxygenase and topoisomerase I and Iia shows antitumor and anti-inflammatory activities

Additional Information

MDL Number	MFCD03788773
ChemACX	X1551440-4
InChI	InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32-/m1/s1
SMILES	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C