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Aurintricarboxylic acid

品牌：AG Scientific

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規(guī)格：1 g

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CAS:4431-00-9Formula:C22H14O9MW:422.4Appearance:Red-brownSolidPurity:85%

商品詳情參考文獻相關資料

Inhibits apoptosis in various cell types induced by a variety of factors. Potent inhibitor of DNA topoisomerase II in vitro and protein-nucleic acid interactions. Stimulates the tyrosine phosphorylation of MAP kinases. Inhibits major calpain isoforms.

Additional Information

Synonyms	ATA
Product #	A-2191
CAS #	4431-00-9
Chemical Name	5-[(3-CARBOXY-4-HYDROXYPHENYL)-(3-CARBOXY-4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE)METHYL]-2-HYDROXYBENZOIC ACID
Formula	C₂₂H₁₄O₉
MW	422.4
Appearance	Red-brown Solid
Purity	85%
Solubility	Soluble in water (7 mg/mL), 1 M NH4OH (10 mg/mL), ethanol (60 mg/mL), 0.1 M NaOH (35 mg/mL), and aqueous alkali.
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells

Additional Information

MDL Number	MFCD00011663
ChemACX	X1029883-2
InChI	InChI=1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)
SMILES	c1cc(c(cc1C(=C2C=CC(=O)C(=C2)C(=O)O)c3ccc(c(c3)C(=O)O)O)C(=O)O)O

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