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Analog of kenpaullone acting as a potent and ATP-competitive inhibitor of GSK-3 (IC=18 nM). Displays ~100-200 fold greater selectivity on GSK-3Beta than over CDK1/cyclin B and CDK5/p25 (IC=2.0M and 4.2M, respectively).

Additional Information

Product #	A-1312
CAS #	676596-65-9
Chemical Name	9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
Formula	C15H10BrN3O
MW	328.2
Appearance	Off-white to tan Powder
Purity	95% by HPLC
Solubility	Soluble in DMSO; insoluble in water.
Storage Temp	-20°C

Additional Information

MDL Number	MFCD09037522
InChI	InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
SMILES	c1cc2c(nc1)-c3c(c4cc(ccc4[nH]3)Br)CC(=O)N2