PKC 412 is an inhibitor of serine, threonine,?and tyrosine kinases.?? A potential inhibitor of?FLT-3 kinase, including?mutant forms found in acute myeloid leukemia in vitro and in vivo. Induces?apoptosis.?Selective inhibitor of?T lymphocyte production of TNF-α.??Exhibits?antiproliferative activity against various tumor cell lines.
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