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Cell-permeable. A selective, non-competitive Calpain inhibitor (K = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.

Additional Information

Synonyms	3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Product #	P-2388
Chemical Name	3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Formula	C9H7IO2S
MW	306.12
Appearance	Off-White Solid
Purity	98% by NMR
Solubility	DMSO (10 mg/ml) or EtOH (1 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	PD 150606 is a selective, cell-permeable inhibitor of calpains

Additional Information

MDL Number	MFCD00949076
InChI	InChI=1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-
SMILES	C1=CC(=CC=C1/C=C(/C(=O)O)S)I