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Manumycin A, Streptomyces parvulus

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CAS:52665-74-4Formula:C31H38N2O7MW:550.7Appearance:YellowSolidPurity:96%(HPLC)

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A potent and selective inhibitor of Ras farnesyltransferase.

Product #	M-1052
CAS #	52665-74-4
Chemical Name	(2E,4E,6R)-N-[(1S,5S,6R)-5-HYDROXY-5-((1E,3E,5E)-7-[(2-HYDROXY-5-OXO-1-CYCLOPENTEN-1-YL)AMINO]-7-OXO-1,3,5-HEPTATRIEN-1-YL)-2-OXO-7-OXABICYCLO[4.1.0]HEPT-3-EN-3-YL]-2,4,6-TRIMETHYL-2,4-DECADIENAMIDE
Formula	C₃₁H₃₈N₂O₇
MW	550.7
Appearance	Yellow Solid
Purity	96% (HPLC)
Solubility	Soluble in 100% ethanol; slightly soluble in chloroform.
Storage Temp	+4°C Short term.-20°C long term
Therapeutic Area	Oncological Disorders
Use	A potent and selective inhibitor of Ras farnesyltransferasein cancer

MDL Number	MFCD00920782
ChemACX	X1093234-6
InChI	InChI=1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,28-29,34,39H,5-6,11,13-14H2,1-4H3,(H,32,38)(H,33,36)/b8-7+,12-9+,15-10+,20-16+,21-17+/t19-,28-,29-,31+/m1/s1
SMILES	CCCC[C@@H](C)/C=C(C)/C=C(C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O

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